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HomeHealthLLUH trauma center among eight chosen for international study

LLUH trauma center among eight chosen for international study

Researchers at Loma Linda University Health (LLUH) Level I Trauma Center are participating in an international observational clinical study to determine how partial resuscitative endovascular balloon occlusion of the aorta, or partial REBOA, could increase trauma patients’ chances of survival from non-compressible torso hemorrhage (NCTH) by buying time to treat.

This study is funded by the United States Army Medical Research and Development Command (USAMRDC) to fix one of the most important medical challenges on the battlefield and at home – death from NCTH.

LLUH was chosen by the USAMRDC to participate in this study along with seven other leading Level I Trauma Centers across the United States and Canada.

The trauma team at LLUH already performs partial REBOA to help stop a patient’s internal bleeding through a device called pREBOA-PROTM (Prytime Medical Devices, Inc., Boerne, TX). Now the team will participate in the clinical study, called the PROMPT (Partial REBOA Outcomes Multicenter ProspecTive) Study, to share prospective data about the use of the device.

There are four key endpoints of the PROMPT Study:

  1. Time of occlusion
  2. Ischemic markers
  3. Tolerance of reperfusion
  4. Blood pressure

“The PROMPT study may one day change how sick trauma patients are cared for worldwide,” said Kaushik Mukherjee, MD, MSCI, FACS, trauma medical director and division chief of Acute Care Surgery at Loma Linda University Health.

The PROMPT study will provide the trauma community with in-depth clinical data by enrolling 340 patients in two years across all eight selected centers. LLUH patients matching the inclusion criteria have been automatically enrolled in the study since September 2024.

Loma Linda University Health’s Level I Trauma Center cared for 3,300 injured patients in 2023 and has been verified as an Adult and Pediatric Level I Trauma Center since 2018.

Loma Linda
Loma Linda
Loma Linda University Health includes Loma Linda University's eight professional schools, Loma Linda University Medical Center's six hospitals — including The Dennis and Carol Troesh Medical Campus, which opened in August 2021, housing the new adult hospital and Children’s Hospital expansion — and more than 1,000 faculty physicians located in the Inland Empire of Southern California. Established in 1905, Loma Linda University Health is a global leader in education, research and clinical care. It offers over 100 academic programs and provides quality health care to over 40,000 inpatients and 1.5 million outpatients each year. A Seventh-day Adventist organization, Loma Linda University Health is a faith-based health system with a mission "to continue the teaching and healing ministry of Jesus Christ."
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